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home research publications people contact home research publications people contact search: understanding rna-mediated gene regulation in bacteria welcome to the darfeuille lab the main objectives of the d-lab are the identification and characterization of small non-coding rnas associated with the infection by the major human gastric pathogen helicobacter pylori . we seek to understand the molecular and biochemical basis of rna-based regulation of key genes involved in the pathogenicity and/or metabolism of this bacterium. in collaboration with rna chemists, our group also aims at the identification of small compounds able to interfere with the biogenesis and regulation of small rnas. we hope that our research will help to develop alternative strategies to fight against drug resistance, both, in the field of cancer as well as in bacterial infections ( antibiotic resistance ). discover our lab our research research our papers publications meet the team people news ! 5th meeting of regulating with rna in bacteria & archaea: rna2018 the d-lab is back from a ‘wonder-full’ week at the 5th meeting of regulating with rna in bacteria & archaea: rna2018 in seville, spain ! an intense and enriching experience; a celebration of the ‘infinite’ processes of life !... 24 mars, 2018 welcome on board delphine ! delphine bronesky (phd student, université de strasbourg, architecture de l’arn et réactivité, ibmc, under the supervision of p. romby and i. caldelari) has recently joined the lab ! she will start a new project in the group, that consist in turning on the expression of toxin-antitoxin...... 09 mars, 2018 cauterets february 2018 ! the d-lab is just back from the traditional 3-days lab retreat in the pyrénées ! a great occasion to get to know about the last and most exciting research going on in each of the teams composing this astonishing unit ! .. and, of course, have some fun !...... 04 février, 2018 the d-lab keeps up with: new approaches and concepts in microbiology embl symposia in heidelberg ! this week we are traveling to germany to attend to the new approaches and concepts in microbiology symposia at the embl heidelberg. great exchange opportunity, keeping up with the latests advances on the microbiology field ! ... 29 juin, 2017 see our latest article published on-line on january 10th, 2017 ! our lastest paper is now published online in nucleic acids research ! please visit nar advance access a new toxin antitoxin system was discovered in the human gastric pathogen helicobacter pylori. this new ta system is actually conserved in many epsilon proteobacteria. it...... 17 janvier, 2017 merry christmas from the d-lab! with 2016 coming to its end, from the d-lab we wish you an intense new year 2017, full of energy, creativity and vision!... 24 décembre, 2016 3rd metarna itn workshop on metabolism- 7 to 11 november 2016, groningen last week our student sara masachis gelo travelled to groningen to attend the 3rd workshop of the metarna itn network. in this occasion, the fellows had the opportunity to expand their knowledge on metabolomics, metabolic fluxes and kinetic modelling guided by the coordinator, prof. dr....... 20 novembre, 2016 welcome sara to the d-lab ! sara masachis gelo (recruited in the eu research-training network metarna) recently joined the d-lab to start her phd. she will engeneer rna-based expression systems to monitor metabolic changes in living cells. please find more infos about sara: https://metarna.wordpress.com/2016/01/09/meet-the-fellows/ ... 03 avril, 2016 they didn't know it was impossible so they did it ! mark twain our sponsors credits legal useful links © darfeuille lab 2016

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